Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (rear for the Mercedes Benz and 4 x 4 in the case of the Audi). The first one has a Mercedes Benz-engineered powertrain under the hood, a 8-cylinder, 32-valves 525hp unit, while the other one gets its power and torque from a 8-cylinder, 32-valves 420hp engine designed by Volkswagen.

A starting point here would be to take a look at the results from European New Car Assessment Programme (Euro NCAP) tests which were performed on both of the cars, with the same number of safety stars gained in the process. Still, apart from the official crash test results there are other things we need to be aware of. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, still it doesn't help us solve our dilemma, does it? On the other hand, when it comes to weight, a factor that most people underestimate, Audi A6 offers a marginal difference of 7% more metal.

I don't like generalizing things when it comes to reliability, although it does seem that both brands display similar results in faults and breakdowns, when all the models are taken into account. That's the official data, while our visitors describe reliability of Mercedes Benz with an average rating of 4.3, and models under the Audi badge with 4.2 out of 5. Independent research findings rank E as average reliability-wise, and A6 is more or less at the same level.Above it all, drivers of cars with the same engine as Mercedes Benz E rank it on average as 3.0 out of 5, exactly the same as the other one.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.1 seconds less than its competitor. Still, it lacks the power to win the top speed competition, topping at 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy an obvious choice would be Audi A6, averaging around 9.6 liters of fuel per 100 kilometers (29 mpg), in combined cycle. That's 31% difference compared to Mercedes Benz E!

Mercedes Benz appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, Audi A6 offers slightly better overall protection and takes the lead. From there things take a different direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. It does come at a cost though, and that's the fuel consumption... All together, there's not much more to say, in this case I wouldn't even consider anything but Audi. Nevertheless, let's not forget that people have different preferences and needs, so what really counts is your personal feel. I'm only here to help. Also, you could use the oportunity to find out which car, everything taken into account, would be the perfect choice for you in the eyes of the virtual adviser™, among more than 12.000 different ones in our database.