Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (rear for the Mercedes Benz and 4 x 4 in the case of the Audi). The first one has a Mercedes Benz-engineered powertrain under the hood, a 8-cylinder, 32-valves 525hp unit, while the other one gets its power and torque from a 8-cylinder, 32-valves 420hp engine designed by Volkswagen.

The first thing to look into here would be the results from European New Car Assessment Programme (Euro NCAP) tests performed on the two cars. Good thing is that both vehicles got tested, with the same number of safety stars gained in the process. Still, apart from the official crash test results there are other things we need to be aware of. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but that fact doesn't break the tie between the two cars. On the other hand, taking kerb weight as an important factor into account, Audi A6 offers a marginal difference of 7% more metal.

Manufacturers have been building their reliability reputation for decades now and, generally speaking, it appears that both brands display similar results in faults and breakdowns, when all the models are taken into account. These are the results of an independent reasearch, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Audi badge with 4.2 out of 5. Independent research findings rank E as average reliability-wise, and A6 is more or less at the same level.Above it all, drivers of cars with the same engine as Mercedes Benz E rank it on average as 3.0 out of 5, exactly the same as the other one.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.1 seconds less than its competitor. Still, it lacks the power to win the top speed competition, topping at 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy an obvious choice would be Audi A6, averaging around 9.6 liters of fuel per 100 kilometers (29 mpg), in combined cycle. That's 31% difference compared to Mercedes Benz E!

Mercedes Benz appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, Audi A6 offers slightly better overall protection and takes the lead. From there things take a different direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. It does come at a cost though, and that's the fuel consumption... All together, there's not much more to say, in this case I wouldn't even consider anything but Audi. Anyway, that's the most objective conclusion I could've came up with and it's based solely on the information found on this website. Aspects such as design, practicality, brand value and driving experience are there for you to measure them out. Also, you could use the oportunity to find out which car, everything taken into account, would be the perfect choice for you in the eyes of the virtual adviser™, among thousands of similar, yet so different vehicles.