Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (rear for the Mercedes Benz and 4 x 4 in the case of the Audi). The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 24-valves 306hp unit, while the other one gets its power and torque from a 8-cylinder, 32-valves 420hp engine designed by Volkswagen.

A starting point here would be to take a look at the results from European New Car Assessment Programme (Euro NCAP) tests which were performed on both of the cars, with the same number of safety stars gained in the process. Moving further on, let's take a closer look at some additional safety-related facts. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but it doesn't do much to help us decide between the two. On the other hand, if we'd like to consider vehicle mass in this context too, which we definitely should, Audi A6 offers a considerable difference of 14% more metal.

I don't like generalizing things when it comes to reliability, although it does seem that both brands display similar results in faults and breakdowns, all the models observed together. That's the official data, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Audi badge with 4.2 out of 5. Some independent research have also placed E as average reliability-wise, and A6 is more or less at the same level.Above it all, drivers of cars with the same engine as Mercedes Benz E rank it on average as 5.0, while the one under the competitor's bonnet gets 3.0 out of 5.

Audi is undoubtly more agile, reaching 100km/h in 1.7 seconds less than its competitor. In addition to that it accelerates all the way to 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy an obvious choice would be Mercedes Benz E, averaging around 6.8 liters of fuel per 100 kilometers (42 mpg), in combined cycle. That's 41% difference compared to Audi A6!

Mercedes Benz appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, Audi A6 offers significantly better overall protection, taking the lead here. It all continues in the same direction, with Audi being considerably quicker, thus putting more smile on driver's face. It does come at a cost though, and that's the fuel consumption... I believe that, when we take all into account, we have only one winner here - the Mercedes Benz. In any case that's my personal view, built upon all the data available to me. What should decide here though is the way you feel about the two vehicles, and I hope you'll find my guidelines useful in the process. In case you have two minutes to spare I invite you to define your needs, desires and budget and see which car would be chosen by the virtual adviser™, among more than 12.000 different ones in our database.