Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 5-door wagon body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (rear for the Mercedes Benz and 4 x 4 in the case of the Audi). The first one has a Mercedes Benz-engineered powertrain under the hood, a 8-cylinder, 32-valves 408hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 333hp engine designed by Volkswagen.

Both vehicles got tested by European New Car Assessment Programme (Euro NCAP), with the same number of safety stars gained in the process. Moving further on, let's take a closer look at some additional safety-related facts. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, still it doesn't help us solve our dilemma, does it? Furthermore, taking kerb weight as an important factor into account, Mercedes Benz E offers a marginal difference of 6% more metal.

Manufacturers have been building their reliability reputation for decades now and, generally speaking, it appears that both brands display similar results in faults and breakdowns, all the models observed together. That's the official data, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Audi badge with 4.2 out of 5. Independent research findings rank E as average reliability-wise, and A6 is more or less at the same level.Above it all, drivers of cars with the same engine as Mercedes Benz E rank it on average as 3.0, while the one under the competitor's bonnet gets 4.3 out of 5.

Audi is a bit more agile, reaching 100km/h in 0.1 seconds less than its competitor. In addition to that it accelerates all the way to 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy the winner has to be Audi A6, averaging around 7.6 liters of fuel per 100 kilometers (37 mpg), in combined cycle. We can't ignore that 22% difference compared to Mercedes Benz E.

Audi appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, Mercedes Benz E offers slightly better overall protection and takes the lead. From there things take a different direction, with Audi offering somewhat better performance, just enough to call it quicker. To make things even better, it consumps less fuel! All together, there's not much more to say, in this case I wouldn't even consider anything but Audi. In any case that's my personal view, built upon all the data available to me. What should decide here though is the way you feel about the two vehicles, and I hope you'll find my guidelines useful in the process. I suggest you spend two more minutes in order to find out which car, based on your needs and budget, would be picked by the virtual adviser™, among more than 12.000 different ones in our database.