Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 5-door wagon body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (rear for the Mercedes Benz and 4 x 4 in the case of the Audi). The first one has a Mercedes Benz-engineered powertrain under the hood, a 8-cylinder, 32-valves 515hp unit, while the other one gets its power and torque from a 10-cylinder, 40-valves 435hp engine designed by Volkswagen.

The first thing to look into here would be the results from European New Car Assessment Programme (Euro NCAP) tests performed on the two cars. Good thing is that both vehicles got tested, with the same number of safety stars gained in the process. That aside, let's consider some other aspects which affect safety. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but that fact doesn't break the tie between the two cars. On the other hand, taking kerb weight as an important factor into account, Audi A6 offers a marginal difference of 6% more metal.

Reliability is not the best thing to consider on the make level, but it is worth mentioning that both brands display similar results in faults and breakdowns, when all the models are taken into account. That's the official data, while our visitors describe reliability of Mercedes Benz with an average rating of 4.3, and models under the Audi badge with 4.2 out of 5. Some independent research have also placed E as average reliability-wise, and A6 is more or less at the same level.That apart, owners of different cars powered by the same engine as Mercedes Benz E rank it on average as 3.0, while the one under the competitor's bonnet gets 4.0 out of 5.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.7 seconds less than its competitor. Still, it lacks the power to win the top speed competition, topping at 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy the winner has to be Audi A6, averaging around 12.6 liters of fuel per 100 kilometers (22 mpg), in combined cycle. We can't ignore that 15% difference compared to Mercedes Benz E.

Audi appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, Audi A6 offers slightly better overall protection and takes the lead. From there things take a different direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. It does come at a cost though, and that's the fuel consumption... All together, there's not much more to say, in this case I wouldn't even consider anything but Audi. Nevertheless, let's not forget that people have different preferences and needs, so what really counts is your personal feel. I'm only here to help. I suggest you spend two more minutes in order to find out which car, based on your needs and budget, would be picked by the virtual adviser™, among more than 12.000 different ones in our database.