Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (rear for the Mercedes Benz and 4 x 4 in the case of the Audi). The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 24-valves 272hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 290hp engine designed by Volkswagen.

Both vehicles got tested by European New Car Assessment Programme (Euro NCAP), with the same number of safety stars gained in the process. That aside, let's consider some other aspects which affect safety. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but that fact doesn't break the tie between the two cars. On the other hand, if we'd like to consider vehicle mass in this context too, which we definitely should, Audi A6 offers a marginal difference of 8% more metal.

Reliability is not the best thing to consider on the make level, but it is worth mentioning that both brands display similar results in faults and breakdowns, all the models observed together. These are the official statistics, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Audi badge with 4.2 out of 5. The same official information place E as average reliability-wise, and A6 is more or less at the same level.We should definitely mention that owners of cars with the same powertrain as Mercedes Benz E rank it on average as 5.0, while the one under the competitor's bonnet gets 3.6 out of 5.

Audi is undoubtly more agile, reaching 100km/h in 1 seconds less than its competitor. In addition to that it accelerates all the way to 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy things look pretty much the same for both cars, averaging around 9.6 liters of fuel per 100 kilometers (30 mpg), in combined cycle.

Mercedes Benz appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, Audi A6 offers slightly better overall protection and takes the lead. It all continues in the same direction, with Audi being considerably quicker, thus putting more smile on driver's face. To make things even better, it consumps less fuel! It's not difficult to say then that if I'd need to make a choice, it would definitely be the Audi. In any case that's my personal view, built upon all the data available to me. What should decide here though is the way you feel about the two vehicles, and I hope you'll find my guidelines useful in the process. In case you have two minutes to spare I invite you to define your needs, desires and budget and see which car would be chosen by the virtual adviser™, among more than 12.000 different ones in our database.