Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (rear for the Mercedes Benz and 4 x 4 in the case of the Audi). The first one has a Mercedes Benz-engineered powertrain under the hood, a 8-cylinder, 24-valves 476hp unit, while the other one gets its power and torque from a 10-cylinder, 40-valves 435hp engine designed by Volkswagen.

A starting point here would be to take a look at the results from European New Car Assessment Programme (Euro NCAP) tests which were performed on both of the cars, with the same number of safety stars gained in the process. Still, apart from the official crash test results there are other things we need to be aware of. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but it doesn't do much to help us decide between the two. On the other hand, when it comes to weight, a factor that most people underestimate, Audi A6 offers a considerable difference of 10% more metal.

Manufacturers have been building their reliability reputation for decades now and, generally speaking, it appears that both brands display similar results in faults and breakdowns, all the models observed together. These are the results of an independent reasearch, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Audi badge with 4.2 out of 5. Independent research findings rank E as average reliability-wise, and A6 is more or less at the same level.We should definitely mention that owners of cars with the same powertrain as Mercedes Benz E rank it on average as 3.0, while the one under the competitor's bonnet gets 4.0 out of 5.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.5 seconds less than its competitor. Still, it lacks the power to win the top speed competition, topping at 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy things look pretty much the same for both cars, averaging around 13.2 liters of fuel per 100 kilometers (21 mpg), in combined cycle.

Audi appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, Audi A6 offers significantly better overall protection, taking the lead here. From there things take a different direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. To make things even better, it consumps less fuel! At the end, as much as I'd like to give you a winner here, it's simply a pure tie if you ask me. Nevertheless, let's not forget that people have different preferences and needs, so what really counts is your personal feel. I'm only here to help. Also, you could use the oportunity to find out which car, everything taken into account, would be the perfect choice for you in the eyes of the virtual adviser™, out of 12.000+ vehicles we currently have in our database.