Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (4 x 4 for the Mercedes Benz and rear in the case of the Lexus). The first one has a Mercedes Benz-engineered powertrain under the hood, a 8-cylinder, 32-valves 388hp unit, while the other one gets its power and torque from a 8-cylinder, 32-valves 348hp engine designed by Toyota.

A starting point here would be to take a look at the results from European New Car Assessment Programme (Euro NCAP) tests which were performed on both of the cars, with the same number of safety stars gained in the process. Still, apart from the official crash test results there are other things we need to be aware of. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but it doesn't do much to help us decide between the two. Furthermore, when it comes to weight, a factor that most people underestimate, the German car offers a marginal difference of 4% more metal.

Manufacturers have been building their reliability reputation for decades now and, generally speaking, it appears that Lexus as a brand displays somewhat better results, all the models observed together. These are the results of an independent reasearch, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Lexus badge with 4.9 out of 5. Independent research findings rank E as average reliability-wise, and GS is more or less at the same level.We should definitely mention that owners of cars with the same powertrain as the German car rank it on average as 5.0, while the one under the competitor's bonnet gets 3.0 out of 5.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.4 seconds less than its competitor. Still, it lacks the power to win the top speed competition, topping at 250 kilometers per hour, exactly the same as the other car does. When it comes to fuel economy things look pretty much the same for both cars, averaging around 11 liters of fuel per 100 kilometers (26 mpg), in combined cycle.

Mercedes Benz appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, the German car offers slightly better overall protection and takes the lead. It all continues in the same direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. Fuel consumption is more or less the same. No mistake, whatever you decide here, but I'd still go for the Mercedes Benz. Nevertheless, let's not forget that people have different preferences and needs, so what really counts is your personal feel. I'm only here to help. I suggest you spend two more minutes in order to find out which car, based on your needs and budget, would be picked by the virtual adviser™, among thousands of similar, yet so different vehicles.