Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (4 x 4 for the Mercedes Benz and rear in the case of the Lexus). The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 24-valves 306hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 252hp engine designed by Toyota.

A starting point here would be to take a look at the results from European New Car Assessment Programme (Euro NCAP) tests which were performed on both of the cars, with the same number of safety stars gained in the process. Moving further on, let's take a closer look at some additional safety-related facts. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but it doesn't do much to help us decide between the two. Furthermore, if we'd like to consider vehicle mass in this context too, which we definitely should, the German car offers a marginal difference of 8% more metal.

Manufacturers have been building their reliability reputation for decades now and, generally speaking, it appears that Lexus as a brand displays somewhat better results, all the models observed together. These are the results of an independent reasearch, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Lexus badge with 4.9 out of 5. Independent research findings rank E as average reliability-wise, and GS is more or less at the same level.We should definitely mention that owners of cars with the same powertrain as the German car rank it on average as 5.0 out of 5, exactly the same as the other one.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.6 seconds less than its competitor. In addition to that it accelerates all the way to 250 kilometers per hour, 10km/h more than the other car. When it comes to fuel economy an obvious choice would be the German car, averaging around 7.4 liters of fuel per 100 kilometers (38 mpg), in combined cycle. That's 28% difference compared to the Japanese car!

Lexus appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, the German car offers slightly better overall protection and takes the lead. It all continues in the same direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. To make things even better, it consumps less fuel! All together, there's not much more to say, in this case I wouldn't even consider anything but Mercedes Benz. Nevertheless, let's not forget that people have different preferences and needs, so what really counts is your personal feel. I'm only here to help. In case you have two minutes to spare I invite you to define your needs, desires and budget and see which car would be chosen by the virtual adviser™, among more than 12.000 different ones in our database.