Well, these are two pretty similar cars we have here! It's only details that could potentially make the difference. Considering they both belong to the luxury car segment and utilize the same 4-door sedan body style and the rear wheel drive system, it all comes up to the specific petrol engine choice they offer. The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 24-valves 306hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 252hp engine designed by Toyota.

A starting point here would be to take a look at the results from European New Car Assessment Programme (Euro NCAP) tests which were performed on both of the cars, with the same number of safety stars gained in the process. That aside, let's consider some other aspects which affect safety. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, still it doesn't help us solve our dilemma, does it? Furthermore, when it comes to weight, a factor that most people underestimate, the German car offers a marginal difference of 3% more metal.

Reliability is not the best thing to consider on the make level, but it is worth mentioning that Lexus as a brand displays somewhat better results, when all the models are taken into account. These are the results of an independent reasearch, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Lexus badge with 4.9 out of 5. The same official information place E as average reliability-wise, and GS is more or less at the same level.That apart, owners of different cars powered by the same engine as the German car rank it on average as 5.0 out of 5, exactly the same as the other one.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.9 seconds less than its competitor. In addition to that it accelerates all the way to 250 kilometers per hour, 10km/h more than the other car. When it comes to fuel economy an obvious choice would be the German car, averaging around 6.8 liters of fuel per 100 kilometers (42 mpg), in combined cycle. That's 40% difference compared to the Japanese car!

Lexus appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, the German car offers slightly better overall protection and takes the lead. It all continues in the same direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. To make things even better, it consumps less fuel! All together, there's not much more to say, in this case I wouldn't even consider anything but Mercedes Benz. In any case that's my personal view, built upon all the data available to me. What should decide here though is the way you feel about the two vehicles, and I hope you'll find my guidelines useful in the process. I suggest you spend two more minutes in order to find out which car, based on your needs and budget, would be picked by the virtual adviser™, among thousands of similar, yet so different vehicles.