Well, these are two pretty similar cars we have here! It's only details that could potentially make the difference. Considering they both belong to the luxury car segment and utilize the same 4-door sedan body style and the rear wheel drive system, it all comes up to the specific petrol engine choice they offer. The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 24-valves 231hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 252hp engine designed by Toyota.

A starting point here would be to take a look at the results from European New Car Assessment Programme (Euro NCAP) tests which were performed on both of the cars, with the same number of safety stars gained in the process. Still, apart from the official crash test results there are other things we need to be aware of. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but it doesn't do much to help us decide between the two. On the other hand, if we'd like to consider vehicle mass in this context too, which we definitely should, the Japanese car offers a marginal difference of 2% more metal.

Reliability is not the best thing to consider on the make level, but it is worth mentioning that Lexus as a brand displays somewhat better results, all the models observed together. These are the official statistics, while our visitors describe reliability of Mercedes Benz with an average rating of 4.3, and models under the Lexus badge with 4.9 out of 5. Some independent research have also placed E as average reliability-wise, and GS is more or less at the same level.That apart, owners of different cars powered by the same engine as the German car rank it on average as 4.5, while the one under the competitor's bonnet gets 5.0 out of 5.

Lexus is a bit more agile, reaching 100km/h in 0.1 seconds less than its competitor. Still, it lacks the power to win the top speed competition, topping at 240 kilometers per hour, 10km/h less than the other car. When it comes to fuel economy things look pretty much the same for both cars, averaging around 9.6 liters of fuel per 100 kilometers (30 mpg), in combined cycle.

Lexus appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, the Japanese car offers slightly better overall protection and takes the lead. From there things take a different direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. To make things even better, it consumps less fuel! It's really tough to make a final decision here, but if I'd need to, I'd say Mercedes Benz. Nevertheless, let's not forget that people have different preferences and needs, so what really counts is your personal feel. I'm only here to help. I suggest you spend two more minutes in order to find out which car, based on your needs and budget, would be picked by the virtual adviser™, among thousands of similar, yet so different vehicles.