Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Luxury car' segment, the only major difference here really is their wheel drive configuration (4 x 4 for the Mercedes Benz and rear in the case of the Lexus). The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 24-valves 231hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 220hp engine designed by Toyota.

The fact that the Mercedes Benz got tested by the European New Car Assessment Programme (Euro NCAP), while the other contender didn't, puts it sky-high safety-wise, in my eyes at least. That aside, let's consider some other aspects which affect safety. Both vehicles belong to the luxury car segment, which is generally a very good thing safety-wise, but that fact doesn't break the tie between the two cars. Furthermore, taking kerb weight as an important factor into account, the German car offers a marginal difference of 2% more metal.

I don't like generalizing things when it comes to reliability, although it does seem that Lexus as a brand displays somewhat better results, all the models observed together. That's the official data, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Lexus badge with 4.9 out of 5. Unfortunatelly, I don't have enough insight that would allow me to comment in more details on the specific models level. We should definitely mention that owners of cars with the same powertrain as the German car rank it on average as 4.0, while the one under the competitor's bonnet gets 3.0 out of 5.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.4 seconds less than its competitor. In addition to that it accelerates all the way to 244 kilometers per hour, 14km/h more than the other car. When it comes to fuel economy the winner has to be the German car, averaging around 9.9 liters of fuel per 100 kilometers (29 mpg), in combined cycle. We can't ignore that 17% difference compared to the Japanese car.

Lexus appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, the German car beats the other contender by far, making it the best choice without even considering other things. It all continues in the same direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. To make things even better, it consumps less fuel! All together, there's not much more to say, in this case I wouldn't even consider anything but Mercedes Benz. Anyway, that's the most objective conclusion I could've came up with and it's based solely on the information found on this website. Aspects such as design, practicality, brand value and driving experience are there for you to measure them out. Also, you could use the oportunity to find out which car, everything taken into account, would be the perfect choice for you in the eyes of the virtual adviser™, among thousands of similar, yet so different vehicles.