Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Large family car' segment, the only major difference here really is their wheel drive configuration (4 x 4 for the Mercedes Benz and rear in the case of the Lexus). The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 18-valves 218hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 207hp engine designed by Toyota.

Both vehicles got tested by European New Car Assessment Programme (Euro NCAP), with the same number of safety stars gained in the process. Moving further on, let's take a closer look at some additional safety-related facts. Both vehicles belong to the large family car segment, which is generally a good thing safety-wise, still it doesn't help us solve our dilemma, does it? Furthermore, if we'd like to consider vehicle mass in this context too, which we definitely should, the Japanese car offers a marginal difference of 1% more metal.

I don't like generalizing things when it comes to reliability, although it does seem that Lexus as a brand displays somewhat better results, all the models observed together. That's the official data, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Lexus badge with 4.9 out of 5. Independent research findings rank C as average reliability-wise, and IS is more or less at the same level.That apart, owners of different cars powered by the same engine as the German car rank it on average as 4.6, while the one under the competitor's bonnet gets 5.0 out of 5.

Mercedes Benz is a bit more agile, reaching 100km/h in 0.1 seconds less than its competitor. In addition to that it accelerates all the way to 245 kilometers per hour, 15km/h more than the other car. When it comes to fuel economy the winner has to be the Japanese car, averaging around 9.8 liters of fuel per 100 kilometers (29 mpg), in combined cycle. We can't ignore that 9% difference compared to the German car.

Lexus appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, the Japanese car offers slightly better overall protection and takes the lead. From there things take a different direction, with Mercedes Benz offering somewhat better performance, just enough to call it quicker. It does come at a cost though, and that's the fuel consumption... All together, there's not much more to say, in this case I wouldn't even consider anything but Lexus. Nevertheless, let's not forget that people have different preferences and needs, so what really counts is your personal feel. I'm only here to help. I suggest you spend two more minutes in order to find out which car, based on your needs and budget, would be picked by the virtual adviser™, among thousands of similar, yet so different vehicles.