Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Large family car' segment, the only major difference here really is their wheel drive configuration (rear for the Lexus and 4 x 4 in the case of the Mercedes Benz). The first one has a Toyota-engineered powertrain under the hood, a 6-cylinder, 24-valves 207hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 333hp engine designed by Mercedes Benz.

Both vehicles got tested by European New Car Assessment Programme (Euro NCAP), with the same number of safety stars gained in the process. That aside, let's consider some other aspects which affect safety. Both vehicles belong to the large family car segment, which is generally a good thing safety-wise, but it doesn't do much to help us decide between the two.

I don't like generalizing things when it comes to reliability, although it does seem that Lexus as a brand displays somewhat better results, when all the models are taken into account. These are the official statistics, while our visitors describe reliability of Lexus with an average rating of 4.9, and models under the Mercedes Benz badge with 4.3 out of 5. The same official information place IS as average reliability-wise, and C is more or less at the same level.Above it all, drivers of cars with the same engine as the Japanese car rank it on average as 5.0 out of 5, exactly the same as the other one.

There's not enough data for me to elaborate on the subject, I'm affraid.

Lexus appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In this case though, it seems that both cars show similar levels of passenger protection all together, so that won't break a tie. When it comes to performance, both vehicles provide similar experience, so I wouldn't point any of them out. Fuel consumption is more or less the same. It's really tough to make a final decision here, but if I'd need to, I'd say Lexus. In any case that's my personal view, built upon all the data available to me. What should decide here though is the way you feel about the two vehicles, and I hope you'll find my guidelines useful in the process. In case you have two minutes to spare I invite you to define your needs, desires and budget and see which car would be chosen by the virtual adviser™, out of 12.000+ vehicles we currently have in our database.