Two significantly similar cars, no doubt about that. Still, each one has something different to offer. Having both cars powered by petrol engines and utilizing the 4-door sedan body style within the same 'Large family car' segment, the only major difference here really is their wheel drive configuration (4 x 4 for the Mercedes Benz and rear in the case of the Lexus). The first one has a Mercedes Benz-engineered powertrain under the hood, a 6-cylinder, 24-valves 272hp unit, while the other one gets its power and torque from a 6-cylinder, 24-valves 207hp engine designed by Toyota.

Both vehicles got tested by European New Car Assessment Programme (Euro NCAP), with the same number of safety stars gained in the process. That aside, let's consider some other aspects which affect safety. Both vehicles belong to the large family car segment, which is generally a good thing safety-wise, but that fact doesn't break the tie between the two cars. Furthermore, if we'd like to consider vehicle mass in this context too, which we definitely should, the German car offers a marginal difference of 1% more metal.

Manufacturers have been building their reliability reputation for decades now and, generally speaking, it appears that Lexus as a brand displays somewhat better results, at least on all of the models level. These are the official statistics, while our visitors describe reliability of Mercedes Benz with an average rating of 4.4, and models under the Lexus badge with 4.9 out of 5. Some independent research have also placed C as average reliability-wise, and IS is more or less at the same level.We should definitely mention that owners of cars with the same powertrain as the German car rank it on average as 5.0 out of 5, exactly the same as the other one.

Mercedes Benz is undoubtly more agile, reaching 100km/h in 1.2 seconds less than its competitor. In addition to that it accelerates all the way to 250 kilometers per hour, 20km/h more than the other car. When it comes to fuel economy things look pretty much the same for both cars, averaging around 10 liters of fuel per 100 kilometers (28 mpg), in combined cycle.

Lexus appears just a bit more reliable, although the difference is truly marginal. The most important thing when deciding between any two vehicles should always be safety, both passive and active. In my opinion, everything taken into account, the German car offers slightly better overall protection and takes the lead. It all continues in the same direction, with Mercedes Benz being considerably quicker, thus putting more smile on driver's face. It does come at a cost though, and that's the fuel consumption... At the end, as much as I'd like to give you a winner here, it's simply a pure tie if you ask me. Anyway, that's the most objective conclusion I could've came up with and it's based solely on the information found on this website. Aspects such as design, practicality, brand value and driving experience are there for you to measure them out. I suggest you spend two more minutes in order to find out which car, based on your needs and budget, would be picked by the virtual adviser™, out of 12.000+ vehicles we currently have in our database.